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Merck

MCL1

myeloid cell leukemia sequence 1 (BCL2-related)

Synonyme:
BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(4170) Summary: This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]
  • Mouse(17210) myeloid cell leukemia sequence 1
  • Rat(60430) myeloid cell leukemia sequence 1
  • sheep(554329) myeloid cell leukemia sequence 1 (BCL2-related)
  • domestic guinea pig(100721658) myeloid cell leukemia sequence 1 (BCL2-related)
  • naked mole-rat(101724340) myeloid cell leukemia sequence 1 (BCL2-related)
  • chicken(395674) myeloid cell leukemia sequence 1 (BCL2-related)
  • dog(403537) myeloid cell leukemia sequence 1 (BCL2-related)
  • domestic cat(493970) myeloid cell leukemia sequence 1 (BCL2-related)
  • cow(788087) myeloid cell leukemia sequence 1 (BCL2-related)

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Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
(±)-Gossypol from cotton seeds, ≥95% (HPLC),
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-MCL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-Mcl-1-Antikörper, Klon RC13, clone RC13, from mouse,
Speziesreaktivität
human
Anwendung
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Mcl-1 Antibody, serum, Chemicon®,
Speziesreaktivität
human
Anwendung
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-MCL1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse
Anwendung
ELISA
western blot
Anti-MCL1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human MCL1,
Spezies
human
MISSION® esiRNA, targeting mouse Mcl1,
Spezies
mouse