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Merck

MAPK1

mitogen-activated protein kinase 1

Synonyme:
ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(5594) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(26413) mitogen-activated protein kinase 1
  • Rat(116590) mitogen activated protein kinase 1
  • Zebrafish(360144) mitogen-activated protein kinase 1
  • domestic cat(101087614) mitogen-activated protein kinase 1
  • cow(327672) mitogen-activated protein kinase 1
  • dog(477575) mitogen-activated protein kinase 1
  • chicken(373953) mitogen-activated protein kinase 1
  • sheep(101115485) mitogen-activated protein kinase 1
  • domestic guinea pig(100715180) mitogen-activated protein kinase 1
  • naked mole-rat(101706099) mitogen-activated protein kinase 1

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ELISA

Produktnummer
Beschreibung
Spezies
Phosphotyrosine MAPK1 / MAPK3 ELISA Kit, ,
Spezies
human
Cell-Based ELISA for detecting phospho-ERK1 / 2 (pThr202 / pTyr204) in cultured cell lines, 96 assays,
Spezies
mouse, rat, human
Cell-Based ELISA Sampler Kit for detecting phospho-ERK1/2 (pThr202/pTyr204), phospho-JNK (pThr183/pTyr185), and phospho-p38 MAPK (pThr180/pTyr182) in cultured cell lines, 192 assays,
Spezies
rat, human, mouse

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-MAPK 1/2 Antibody, from rabbit,
Speziesreaktivität
bovine, canine, human, mouse, rat
Anwendung
immunocytochemistry
immunoprecipitation (IP)

western blot
Milli-Mark® Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate, Milli-Mark®, from rabbit,
Speziesreaktivität
human
Anwendung
flow cytometry
Anti-ERK2 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-phospho-MAP Kinase1/2 Antibody, clone 12D4, Upstate®, from mouse,
Speziesreaktivität
avian, canine, human, mouse, rat
Anwendung
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-MAPK1 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Adenin, ≥99%,
Spezies
human, rat, mouse
Adenin, BioReagent, suitable for cell culture,
Spezies
human, rat, mouse
Adenin, BioReagent, suitable for plant cell culture, ≥99%,
Spezies
human, rat, mouse

Proteins

Produktnummer
Beschreibung
Spezies
ERK2, active, GST tagged human, recombinant, expressed in E. coli, PRECISIO® Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human MAPK1,
Spezies
human