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CASP14

caspase 14, apoptosis-related cysteine peptidase

Synonyme:
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(23581) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008]
  • Mouse(12365) caspase 14
  • Rat(299587) caspase 14
  • naked mole-rat(101720095) caspase 14, apoptosis-related cysteine peptidase
  • domestic guinea pig(100715745) caspase 14, apoptosis-related cysteine peptidase
  • sheep(101120827) caspase 14, apoptosis-related cysteine peptidase
  • chicken(776274) caspase 14, apoptosis-related cysteine peptidase
  • cow(517658) caspase 14, apoptosis-related cysteine peptidase
  • domestic cat(101099027) caspase 14, apoptosis-related cysteine peptidase
  • dog(610460) caspase 14, apoptosis-related cysteine peptidase

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CASP14 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
Anti-Caspase-14 Antibody, from rabbit, purified by affinity chromatography,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Monoclonal Anti-CASP14 antibody produced in mouse, clone 4C9, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence

western blot
Anti-Caspase-14 Antibody, clone 6E2C1, Rabbit Monoclonal, ,
Speziesreaktivität
human, rat
Anwendung
western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human CASP14,
Spezies
human
MISSION® esiRNA, targeting mouse Casp14,
Spezies
mouse