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Merck

CACNA1E

calcium channel, voltage-dependent, R type, alpha 1E subunit

Synonyme:
BII, CACH6, CACNL1A6, Cav2.3
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(777) Summary: Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
  • Mouse(12290) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Rat(54234) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Zebrafish(567702) voltage-dependent R-type calcium channel subunit alpha-1E
  • cow(353113) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • domestic cat(101093985) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • dog(490305) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • chicken(424412) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • naked mole-rat(101701145) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • domestic guinea pig(100716749) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • sheep(101102503) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Domestic Rabbit(100009403) calcium channel, voltage-dependent, R type, alpha 1E subunit

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Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Gabapentin -Lösung, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Gabapentin -Lösung, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CACNA1S antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-CACNA1S antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Monoclonal Anti-Dihydropyridine Receptor (α1 Subunit) antibody produced in mouse, clone 1A, buffered aqueous solution,
Speziesreaktivität
guinea pig, human, mouse, rabbit, rat
Anwendung
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Verapamil -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Amlodipinbesilat, ≥98% (HPLC),
Spezies
human
Amlodipinbesilat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Nicardipin -hydrochlorid, powder, ≥98%,
Spezies
human
Verapamil hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Cacna1e,
Spezies
mouse
MISSION® esiRNA, targeting human CACNA1E,
Spezies
human
MISSION® esiRNA, targeting human CACNA1S,
Spezies
human
MISSION® esiRNA, targeting mouse Cacna1s,
Spezies
mouse