SML3655
LockdownPro
≥97% (HPLC)
Synonym(s):
Tetraethyl 4,4′-((propane-2,2-diylbis(4,1-phenylene))bis(oxy))diphthalate
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About This Item
Empirical Formula (Hill Notation):
C39H40O10
Molecular Weight:
668.73
UNSPSC Code:
12352200
NACRES:
NA.25
Recommended Products
Quality Level
Assay
≥97% (HPLC)
form
(oil or liquid)
color
colorless to yellow
storage temp.
2-8°C
SMILES string
CC(C1=CC=C(C=C1)OC2=CC(C(OCC)=O)=C(C(OCC)=O)C=C2)(C3=CC=C(OC4=CC(C(OCC)=O)=C(C(OCC)=O)C=C4)C=C3)C
Biochem/physiol Actions
LockdownPro, an esterified lockdown analog with better cell permeability, is a cell permeable, potent, and selective allosteric inhibitor of phosphatase PPM1F. LockdownPro potently inhibits tissue invasion by PPM1F-overexpressing human cancer cells. It does not inhibit PPM1F in vitro.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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