SML1853

Kaempferitrin

≥97% (NMR)

• Synonym(s): 3,7-Bis((6-deoxy-α-L-mannopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Kaempferol 3,7-dirhamnoside, Lespedin, Lespenefril, Lespenephryl
• Empirical Formula (Hill Notation): C₂₇H₃₀O₁₄
• CAS Number: 482-38-2
• Molecular Weight: 578.52
• MDL number: MFCD21333499
• UNSPSC Code: 12352200

Properties

• biological source: (Cinnamomum sp.)
• Quality Level: 100
• Assay: ≥97% (NMR)
• form: powder
• storage condition: desiccated; protect from light
• color: white to beige
• storage temp.: −20°C
• SMILES string: OC(C=C1)=CC=C1C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(C4=C(O)C=C(O[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)C=C4O2)=O
• InChI: 1S/C27H30O14/c1-9-17(30)20(33)22(35)26(37-9)39-13-7-14(29)16-15(8-13)40-24(11-3-5-12(28)6-4-11)25(19(16)32)41-27-23(36)21(34)18(31)10(2)38-27/h3-10,17-18,20-23,26-31,33-36H,1-2H3/t9-,10-,17-,18-,20+,21+,22+,23+,26-,27-/m0/s1
• InChI key: PUPKKEQDLNREIM-QNSQPKOQSA-N

Description

Biochem/physiol Actions

Kaempferitrin (Lespenefril) is a naturally-occurring kaempferol glycoside with antimicrobial, antioxidant, and anti-inflammatory activities.

Kaempferitrin is a flavonol glycoside, present in several plants, predominant in Bauhinia. It is known to stimulate insulin signaling pathway and induces glucose uptake, by mediating GLUT4 (glucose transporter 4) translocation to adipocyte membrane.. Kaempferitrin aids in lowering blood glucose level and therefore helps to improve the glycemic condition in diabetic animals.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable