SML1085

Retro-2

≥98% (HPLC)

• Synonym(s): 2,3-Dihydro-2-(5-methyl-2-thienyl)-3-phenyl-4(1H)-quinazolinone
• Empirical Formula (Hill Notation): C₁₉H₁₆N₂OS
• CAS Number: 1429192-00-6
• Molecular Weight: 320.41
• MDL number: MFCD28124399
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825463
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 10 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: O=C1C2=CC=CC=C2NC(C3=CC=C(C)S3)N1C4=CC=CC=C4
• InChI: 1S/C19H16N2OS/c1-13-11-12-17(23-13)18-20-16-10-6-5-9-15(16)19(22)21(18)14-7-3-2-4-8-14/h2-12,18,20H,1H3
• InChI key: BOAPXDSRULBILC-UHFFFAOYSA-N

Description

Application

Retro-2 has been used to estimate retrograde trafficking of Shiga toxin subunit B (STxB)-Cy3.

Biochem/physiol Actions

Retro-2 is a non-toxic inhibitor of the endosome-to-Golgi retrograde transport that selectively protect cells from ricin, cholera toxin, and Shiga-like toxins, without affecting compartment morphology, endogenous retrograde cargos, or other trafficking steps.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable