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SMB00083

Sigma-Aldrich

Sweroside

≥95% (LC/MS-ELSD)

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About This Item

Empirical Formula (Hill Notation):
C16H22O9
CAS Number:
Molecular Weight:
358.34
MDL number:
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.25

Assay

≥95% (LC/MS-ELSD)

form

solid

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@@H](O[C@@H]2OC=C3[C@@H](CCOC3=O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C16H22O9/c1-2-7-8-3-4-22-14(21)9(8)6-23-15(7)25-16-13(20)12(19)11(18)10(5-17)24-16/h2,6-8,10-13,15-20H,1,3-5H2/t7-,8+,10-,11-,12+,13-,15+,16+/m1/s1

InChI key

VSJGJMKGNMDJCI-ZASXJUAOSA-N

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General description

Natural product derived from plant source.
Sweroside is an active component of iridoid glycoside, with a molecular weight of 358.344 Da. It is found in variety of plant species.

Application

Sweroside has been used as a standard in MC-high performance liquid chromatography (HPLC)-ultraviolet (UV) experiment.

Biochem/physiol Actions

Sweroside possesses hepatoprotective, antitumor, antibacterial and antifungal properties. It can be used as a potential therapeutic to treat osteoporosis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hui Sun et al.
Fitoterapia, 84, 174-179 (2012-12-04)
Herbal Fructus Corni is a folk medicine with a long history of safe use for treating osteoporosis in postmenopausal women or elderly men in Asia. Sweroside is a bioactive herbal ingredient isolated from Fructus Corni, which has been widely used
Nilgün Oztürk et al.
Phytotherapy research : PTR, 16(7), 627-631 (2002-11-01)
A methanolic extact of Gentiana lutea ssp. symphyandra roots has been investigated for its possible effects on the central nervous system of mice. At doses of 250 and 500 mg/kg (i.p.), the methanol extract of Gentiana roots caused a significant
Nilgün Oztürk et al.
Planta medica, 72(4), 289-294 (2006-03-25)
Wound healing properties of Gentian (Gentiana lutea ssp. symphyandra) extract and its main constituents, gentiopicroside, sweroside and swertiamarine (compounds 1-3, respectively) were evaluated by comparison with dexpanthenol on cultured chicken embryonic fibroblasts. The extract was also analyzed by HPLC to
Wei-dong Xuan et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 41(11), 1064-1067 (2007-02-01)
To investigate the chemical constituents of water-soluble part of stem of Nauclea officinalis. The compounds were isolated and purified by resins, silica gel, and Sephadex LH20 column chromatography repeatedly, and their structures were identified by spectral analysis. Seven compounds were
Satyendra Suryawanshi et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 858(1-2), 211-219 (2007-09-18)
Extracts from Swertia chirata (family Gentianaceae) have antidiabetics and antioxidant activity, largely attributed to the flavonoids and secoiridoids, which are a major class of functional components in methanolic extracts from aerial part of plants. In order to facilitate analysis of

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