Skip to Content
Merck
All Photos(2)

Key Documents

SAE0073

Sigma-Aldrich

Saponin

Synonym(s):

Surfactant Saponin

Sign Into View Organizational & Contract Pricing


About This Item

EC Number:
UNSPSC Code:
12161902
NACRES:
NA.21

description

non-ionic

Quality Level

composition

Sapogenin content, 20-35%

technique(s)

HPLC: suitable
LC/MS: suitable
protein quantification: suitable

sulfated ash

≤10%

Application

Saponins has been used to permeabilize dendritic cells (DCs) for intracellular staining with antibodies.

Biochem/physiol Actions

Saponins are associated with many biological and pharmacological activities. It is known to stimulate immune response in mammals. Saponins possesses antiviral, antifungal, antitumor, anti-inflammatory, hypoglycemic and hypocholesterolemic effects. It is a potent hemolytic, when injected intravaneously. It is also useful as a surfactant to enhance penetration of proteins and other macromolecules through cell membranes. Saponins have also been used as adjuvants for vaccines.

Packaging

10, 25 g in poly bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation
Gotoh K, et al.
Cell Reports, 25(7), 1800-1815 (2018)
Flavia Radogna et al.
Methods in molecular biology (Clifton, N.J.), 2276, 129-141 (2021-06-02)
Cellular energy metabolism is regulated by complex metabolic pathways. Although anaerobic glycolysis was reported as a primary source of energy in cancer leading to a high rate of lactate production, current evidence shows that the main energy source supporting cancer
Sónia A Pinho et al.
The FEBS journal, 289(17), 5198-5217 (2022-02-26)
Cell culture conditions highly influence cell metabolism in vitro. This is relevant for preclinical assays, for which fibroblasts are an interesting cell model, with applications in regenerative medicine, diagnostics and therapeutic development for personalized medicine, and the validation of ingredients for
Shuang Shen et al.
Aging and disease, 13(6), 1919-1938 (2022-12-06)
Mesenchymal stromal/stem cells (MSCs) have been considered an attractive source of cytotherapy due to their promising effects on treating various diseases. Allogeneic MSCs (allo-MSCs) are extensively used in clinical trials due to their convenient preparation and credible performance. Traditionally, allo-MSCs
Advances in saponin-based adjuvants
Sun HX, et al.
Vaccine, 27(12), 1787-1796 (2009)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service