SAB5702608

Anti-KIF3A Antibody, clone 1C8K4, Rabbit Monoclonal

• Synonym(s): FLA10, KLP-20
• UNSPSC Code: 12352203
• NACRES: NA.46

Properties

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 1C8K4, monoclonal
• form: liquid
• mol wt: 80 kDa
• species reactivity: rat, rat, human
• concentration: 1.15 mg/mL
• technique(s): immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200; western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• immunogen sequence: YQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYLAYTEESLRQSLMKLERPRTSKGKARPKTGRRKRSAKPETVIDSLLQ
• UniProt accession no.: Q9Y496
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... KIF3A(11127)

Description

General description

Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 600-699 of human KIF3A (Q9Y496).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC, IF/ICC

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1