SAB4200566

Anti-KHSRP antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• Synonym(s): Anti-FBP2, Anti-FUBP2, Anti-KH-type splicing regulatory protein, Anti-KSRP, Anti-MGC99676
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen ~82 kDa
• species reactivity: rat, mouse, human
• concentration: ~1.0 mg/mL
• technique(s): immunoprecipitation (IP): 1-2 μg using lysates of human HEK-293T cells; western blot: 0.25-0.50 μg/mL using whole extracts of mouse NIH-3T3 cells
• UniProt accession no.: Q92945
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... KHSRP(8570) ; mouse ... Khsrp(16549) ; rat ... Khsrp(171137)

Description

General description

K-homology type-splicing regulatory protein (KHSRP) is a multifunctional RNA-binding protein. It contains four K homology RNA-binding domains and an unusual C-terminal domain. KHSRP is localized in neural and non-neural cell lines. It is located on the human chromosome at 19p13.3.

Specificity

Anti-KHSRP recognizes human, mouse and rat KHSRP.

Immunogen

synthetic peptide corresponding to an internal region of human KHSRP (GeneID: 8570), conjugated to KLH. The corresponding sequence is identical in rat, mouse, monkey, pig and dog KHSPR.

Application

Anti-KHSRP antibody produced in rabbit may be used in immunoblotting and immunoprecipitation.

Biochem/physiol Actions

K-homology type-splicing regulatory protein (KHSRP) is involved in several cellular processes such as transcription, mRNA localization and alternative pre-mRNA splicing. It is also involved in mRNA decay and microRNA precursor maturation.

Physical form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Storage and Stability

For continuous use, store at 2-8 °C for up to one month. For extended storage freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable