Skip to Content
Merck
All Photos(2)

Documents

S2279

Sigma-Aldrich

3′-Sialyl-Lewis-a tetrasaccharide

Synonym(s):

α-NeuNAc-(2→3)-β-D-Gal-(1→3)-(α-L-Fuc-[1→4])-D-GlcNAc, 3′-SLea

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C31H52N2O23
CAS Number:
92448-22-1
Molecular Weight:
820.74
MDL number:
MFCD00214218
UNSPSC Code:
12352204
PubChem Substance ID:
24899518
NACRES:
NA.32

Quality Level

200

storage temp.

−20°C

SMILES string

CC1OC(OC(C(O)CO)C(OC2OC(CO)C(O)C(OC3(CC(O)C(NC(C)=O)C(O3)C(O)C(O)CO)C(O)=O)C2O)C(NC(C)=O)C=O)C(O)C(O)C1O

InChI

1S/C31H52N2O23/c1-9-18(43)21(46)22(47)28(51-9)54-25(15(42)7-36)24(12(5-34)32-10(2)38)53-29-23(48)27(20(45)16(8-37)52-29)56-31(30(49)50)4-13(40)17(33-11(3)39)26(55-31)19(44)14(41)6-35/h5,9,12-29,35-37,40-48H,4,6-8H2,1-3H3,(H,32,38)(H,33,39)(H,49,50)

InChI key

INZOTETZQBPBCE-UHFFFAOYSA-N

Application

3′-Sialyl-Lewis-a tetrasaccharide has been used to inhibit the binding of 5B1 antibody to Sialyl-Lewisa -polyvalent biotinylated sLea-PAA.

Biochem/physiol Actions

Antigen which supports E-, L-, and P-selectin-dependent adhesion.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

6′-Sialyl-D-lactose Na salt, ≥98.0% (HPLC)

Sigma-Aldrich

40817

6′-Sialyl-D-lactose

Human monoclonal antibodies to sialyl-Lewisa (CA19. 9) with potent CDC, ADCC, and antitumor activity
Sawada R, et al.
Clinical Cancer Research, 17(5), 1024-1032 (2011)
Feizi, T.
Current Opinion in Structural Biology, 3, 701-701 (1993)

Articles

O-Glycans

O-Linked glycoproteins are usually large proteins with a molecular mass of >200 kDa. Glycosylation generally occurs in high-density clusters and may represent as much as 50-80% of the overall mass.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service