RAB1108
Rabbit IL-1 beta ELISA Kit
for cell culture supernatants, plasma, and serum samples
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
Recommended Products
species reactivity
rabbit
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type serum sample(s)
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 45 pg/ml
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
rabbit ... IL1B(100008990)
General description
This enzyme-linked immunosorbent assay (ELISA) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of a target protein in biological samples, such as serum, plasma, cell culture supernatants, urine and/or cell and tissue lysates.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
Biochem/physiol Actions
Interleukin 1 beta (IL-1β) is a proinflammatory cytokine, which is implicated in the induction of various acute and chronic inflammation. IL1B is considered as a potential therapeutic target for disease associated with fibrosis and tissue remodeling. Mutations in IL-1β gene are linked with renal manifestations and renal sequelae in Henoch-Schönlein purpura (HSP).
Other Notes
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Interleukin 1 beta (IL1) rs16944 genetic variant as a genetic marker of severe renal manifestations and renal sequelae in Henoch-Schonlein purpura.
Lopez MR, et al.
Clinical and Experimental Rheumatology, S84-S88 (2016)
Eric G Romanowski et al.
Infection and immunity, 89(8), e0011121-e0011121 (2021-04-07)
In this study, we tested the hypothesis that the conserved bacterial IgaA-family protein, GumB, mediates microbial pathogenesis associated with Serratia marcescens ocular infections through regulation of the Rcs stress response system. The role of the Rcs system and bacterial stress
Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis.
Kolb M
The Journal of Clinical Investigation, 107(12), 1529-1536 (2001)
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