RAB0188
Human FGF-7 ELISA Kit
for serum, plasma, cell culture supernatant and urine
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
Recommended Products
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type cell culture supernatant(s)
sample type plasma
sample type urine
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.5 pg/mL
standard curve range: 0.55-400 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... FGF7(2252)
General description
The Human FGF-7 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human FGF-7 in serum, plasma, cell culture supernatants and urine.
The gene FGF7 (fibroblast growth factor 7) is mapped to human chromosome 15q21.1. The encoded protein belongs to the fibroblast growth factor family and is secreted by mesenchymal cells.
Immunogen
Recombinant Human FGF7
Application
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
FGF7 (fibroblast growth factor 7) is involved in the development of skin and sweat glands, wound healing and cutaneous homeostasis. It controls keratinocyte differentiation and viability by modulating autophagy. FGF7 also participates in embryonic development, tumorigenesis, cell proliferation, migration and differentiation. It is linked with several disorders like nonsyndromic cleft lip and palate, thyroid volume, goiter risk and chronic obstructive pulmonary disease. FGF7 plays an important role in the morphology of developing lungs. Absence of the FGF7 activity decreases airway branching during development. During injury, it is involved in airway repair.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
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FGF7 Over Expression is an Independent Prognosticator in Patients with Urothelial Carcinoma of the Upper Urinary Tract and Bladder
Fan EW, et al.
The Journal of Urology, 194(1), 223-229 (2015)
Oncogenic mutations of ALK kinase in neuroblastoma
Chen Y, et al.
Nature, 455(7215), 971-974 (2008)
Recombinant keratinocyte growth factor 1 in tobacco potentially promotes wound healing in diabetic rats
Feng ZG, et al.
BioMed Research International (2014)
Association between fibroblast growth factor 7 and the risk of chronic obstructive pulmonary disease
Xu SC, et al.
Acta Pharmacologica Sinica, 33(8), 998-1003 (2012)
Role of Keratinocyte Growth Factor in the Differentiation of Sweat Gland-Like Cells From Human Umbilical Cord-Derived Mesenchymal Stem Cells.
Xu Y
Stem Cells Translational Medicine, 5(1), 106-116 (2016)
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