Skip to Content
Merck
All Photos(6)

Key Documents

View All Documentation

I1252

Sigma-Aldrich

DL-Isocitric acid trisodium salt hydrate

≥93%

Synonym(s):

threo-DsLs-Isocitric acid trisodium salt hydrate

Sign Into View Organizational & Contract Pricing
All Photos(6)

About This Item

Empirical Formula (Hill Notation):
C6H5Na3O7 · xH2O
CAS Number:
1637-73-6
Molecular Weight:
258.07 (anhydrous basis)
MDL number:
MFCD00149284
UNSPSC Code:
41116107
PubChem Substance ID:
24895923
NACRES:
NA.25

Assay

≥93%

SMILES string

O.[Na+].[Na+].[Na+].OC(C(CC([O-])=O)C([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3Na.H2O/c7-3(8)1-2(5(10)11)4(9)6(12)13;;;;/h2,4,9H,1H2,(H,7,8)(H,10,11)(H,12,13);;;;1H2/q;3*+1;/p-3

InChI key

BPEHKAXIRZOKIS-UHFFFAOYSA-K

Looking for similar products? Visit Product Comparison Guide

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

An-Ping Lin et al.
Biochemistry, 50(38), 8241-8250 (2011-08-25)
Yeast NAD(+)-specific isocitrate dehydrogenase is an allosterically regulated octameric enzyme composed of four heterodimers of a catalytic IDH2 subunit and a regulatory IDH1 subunit. Despite structural predictions that the enzyme would contain eight isocitrate binding sites, four NAD(+) binding sites
Alexander B Taylor et al.
The Journal of biological chemistry, 283(16), 10872-10880 (2008-02-08)
Mitochondrial NAD(+)-specific isocitrate dehydrogenases (IDHs) are key regulators of flux through biosynthetic and oxidative pathways in response to cellular energy levels. Here we present the first structures of a eukaryotic member of this enzyme family, the allosteric, hetero-octameric, NAD(+)-specific IDH
Metabolism, gliomas, and IDH1.
Jan Smeitink
The New England journal of medicine, 362(12), 1144-1145 (2010-03-26)
Mutations to metabolic enzymes in cancer herald a need to unify genetics and biochemistry.
Akane Kawamura et al.
Cell cycle (Georgetown, Tex.), 10(17), 2819-2820 (2011-08-23)
Grant C Bullock et al.
Blood, 116(1), 97-108 (2010-04-22)
Human red cell differentiation requires the action of erythropoietin on committed progenitor cells. In iron deficiency, committed erythroid progenitors lose responsiveness to erythropoietin, resulting in hypoplastic anemia. To address the basis for iron regulation of erythropoiesis, we established primary hematopoietic
View All Related Papers

Articles

The Krebs cycle — harnessing chemical energy for cellular respiration

Get to know the Tricarboxylic acid (TCA) cycle to better inform your research in biochemistry, metabolomics, or related fields concerned with this metabolic pathway and its enzymes, by-products, or intermediates.

Protocols

Chiral LC-MS/MS of D- and L-2-Hydroxyglutaric Acid Biomarkers

We describe here a rapid and sensitive method to separate and measure D-2-OHG and L-2-OHG enantiomers using high-resolution mass spectrometry (HRMS) detection.

Chromatograms

application for HPLC

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service