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Key Documents

GE17-5182-01

Sigma-Aldrich

SOURCE™ 15S 4.6/100 PE

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About This Item

UNSPSC Code:
41115700
NACRES:
SB.52

ligand

sulfonate group

material

polypropylene column

description

Ion Exchanger Type (value)

packaging

pkg of 1 ea

parameter

580 psi

bed size

4.6 mm × 100 mm

bed volume

1.7 mL

column I.D.

4.6 mm

matrix

polymeric
polystyrene/divinylbenzene

matrix active group

sulphonate phase

avg. part. size

15 μm

cleaning

1-14

working range

2-13

suitability

suitable for bioprocess medium (BioProcess medium. Columns not suitable for use with ÄKTAprime plus system.)

separation technique

cation exchange

General description

SOURCE™ 15S 4.6/100 PE is a strong cation exchanger prepacked in a Tricorn column for intermediate lab-scale purification and large-scale polishing of biomolecules with ion exchange chromatography.

Application

The small (15 μm) monodisperse bead give high-resolution purification at high flow rates. In addition, hydrophilization of the beads minimizes nonspecific adsorption and allows high recovery of purified sample. The material of the column body is PEEK (polyetheretherketone). SOURCE™ 30Q and 30S media with a 30 μm bead size are designed for Intermediate purification and large-scale polishing and allow higher flow rates.

Features and Benefits

  • SOURCE™ 15S media are an excellent choice for fast, high-resolution purifications and easy scale-up
  • Rigid, monodispersed, spherical particles with controlled pore-size distribution offer excellent fLow characteristics, sample loading of up to 25 mg of Protein/mL, and improved stability in organic solvents and pH extremes
  • Improved capacity compared to MonoBeads but with a slightly lower resolution.

Storage and Stability

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
Store at 4 to 30 °C (0.2 M sodium acetate in 20% ethanol)
Store at 4 to 30 °C (20% Ethanol + 0.2 M Sodium Acetate)

Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

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Legal Information

SOURCE is a trademark of Cytiva

Pictograms

Flame
GHS02

Signal Word

Warning

Hazard Statements

H226

Storage Class Code

3 - Flammable liquids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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