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G0545

Sigma-Aldrich

Anti-GABAA Receptor (γ2 subunit) (extracellular) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-γ-Aminobutyric Acid Type A Receptor (γ2 subunit)

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About This Item

MDL number:
MFCD06798448
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

bovine, mouse, rat, human

technique(s)

western blot: 1:200 using rat brain membrane

UniProt accession no.

P18507

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GABRG2(2566)
mouse ... Gabrg2(14406)
rat ... Gabrg2(29709)

Immunogen

synthetic peptide corresponding to amino acids 39-53 of rat GABAA receptor (γ2 subunit). The sequence is identical in human, mouse, and bovine. In chick, it is 13/15 residues identical.

Physical form

Lyophilized from phosphate buffered saline, pH 7.4, 1% BSA, and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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David F Owens et al.
Nature reviews. Neuroscience, 3(9), 715-727 (2002-09-05)
In the mature brain, GABA (gamma-aminobutyric acid) functions primarily as an inhibitory neurotransmitter. But it can also act as a trophic factor during nervous system development to influence events such as proliferation, migration, differentiation, synapse maturation and cell death. GABA
Esa R Korpi et al.
Progress in neurobiology, 67(2), 113-159 (2002-07-20)
Neurotransmitter receptor systems have been the focus of intensive pharmacological research for more than 20 years for basic and applied scientific reasons, but only recently has there been a better understanding of their key features. One of these systems includes
Carolina A Oliva et al.
International journal of molecular sciences, 24(2) (2023-01-22)
In Octodon degus, the aging process is not equivalent between sexes and worsens for females. To determine the beginning of detrimental features in females and the ways in which to improve them, we compared adult females (36 months old) and
Ann J Johnston et al.
Neurobiology of disease, 64, 131-141 (2014-01-11)
Genetic mutations in voltage-gated and ligand-gated ion channel genes have been identified in a small number of Mendelian families with genetic generalised epilepsies (GGEs). They are commonly associated with febrile seizures (FS), childhood absence epilepsy (CAE) and particularly with generalised

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