C0279
Carboxypeptidase Inhibitor from potato tuber
lyophilized powder
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About This Item
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biological source
plant (white russett potato)
form
lyophilized powder
potency
1.1-6.0 nM Ki [CPB]
1.5-3.5 nM Ki [CPA]
mol wt
apparent mol wt 4.075-4.333 kDa
composition
Protein, ≥35% Lowry
solubility
water: soluble 5 mg/mL, clear
storage temp.
−20°C
Biochem/physiol Actions
Broad-spectrum inhibitor of carboxypeptidases of animal digestive-tract origin, but little or no activity against plant and microbial carboxypeptidases. However, recent results suggest it may play a part in resistance to microbial pathogens by preventing digestion of protein.
Packaging
Package size based on protein content
Unit Definition
One μg of inhibitor protein will inhibit the activity of ≥3 μg of carboxypeptidase A by 50% using hippuryl-L-phenylalanine as substrate at pH 7.5 at 25°C.
Physical form
Lyophilized powder containing traces of sodium citrate and sodium chloride; balance primarily non-protein components.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Purification and properties of a carboxypeptidase inhibitor from potatoes.
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The Journal of biological chemistry, 249(17), 5495-5499 (1974-09-10)
David Thompson et al.
The Journal of biological chemistry, 284(37), 24891-24903 (2009-07-11)
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