69602

4-Methylumbelliferyl-β-D-glucuronide hydrate

β-glucuronidase substrate, fluorogenic, ≥99.0% (HPLC), powder or crystals, suitable for fluorescence

• Synonym(s): 4-Methylumbelliferyl-β-D-glucopyranosiduronic acid, MUG
• Empirical Formula (Hill Notation): C₁₆H₁₆O₉ · xH₂O
• CAS Number: 881005-91-0
• Molecular Weight: 352.29 (anhydrous basis)
• EC Number: 228-186-0
• MDL number: MFCD09039280
• UNSPSC Code: 12352204
• PubChem Substance ID: 57652201
• NACRES: NA.32

Properties

• product name: 4-Methylumbelliferyl-β-D-glucuronide hydrate, suitable for fluorescence, ≥99.0% (HPLC)
• Assay: ≥99.0% (HPLC)
• form: powder or crystals
• impurities: ≤0.1% free 4-Methylumbelliferone; ≤15% water
• solubility: DMSO: 50 mg/mL, clear, colorless to very faintly yellow
• fluorescence: λ_ex 365 nm; λ_em 445 nm in 0.1 M phosphate pH 6.5
• suitability: suitable for fluorescence
• storage temp.: −20°C
• SMILES string: O.CC1=CC(=O)Oc2cc(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)ccc12
• InChI: 1S/C16H16O9.H2O/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22;/h2-5,11-14,16,18-20H,1H3,(H,21,22);1H2/t11-,12-,13+,14-,16+;/m0./s1
• InChI key: URVSQZMOFUEQAW-YYHOVTOASA-N

Description

General description

4-Methylumbelliferyl-β-D-glucuronide hydrate (MUG) is a fluorogenic substrate.

Application

4-Methylumbelliferyl-β-D-glucuronide hydrate (MUG) has been used:

• as a β-glucuronidase (GUS) substrate for fluorimetric analysis of reporter gene expression in Arabidopsis thaliana
• for the fluorimetric assay for GUS activity
• to measure liposome lysis by n-octylglucoside

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves