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M9784

Supelco

Mersalyl acid

analytical standard

Synonym(s):

2-(3-Hydroxymercurio-2-methoxypropylcarbamoyl)phenoxyacetic acid, 2-[N-(3-Hydroxymercuri-2-methoxypropyl)carbamoyl]phenoxyacetic acid, Salyrganic acid

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About This Item

Linear Formula:
HOHgCH2CH(OCH3)CH2NHCOC6H4OCH2CO2H
CAS Number:
486-67-9
Molecular Weight:
483.87
EC Number:
207-637-5
MDL number:
MFCD00004302
UNSPSC Code:
41116107
PubChem Substance ID:
329818097
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥85% (TLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

192-193 °C (dec.) (lit.)

solubility

NH4OH: soluble, clear to hazy

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

COC(CNC(=O)c1ccccc1OCC(O)=O)C[Hg]O

InChI

1S/C13H16NO5.Hg.H2O/c1-9(18-2)7-14-13(17)10-5-3-4-6-11(10)19-8-12(15)16;;/h3-6,9H,1,7-8H2,2H3,(H,14,17)(H,15,16);;1H2/q;+1;/p-1

InChI key

HQRSUIDICNOLPX-UHFFFAOYSA-M

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCM8184
MKCL8263
MKBZ4447V
MKBW8949V
MKBR1819V

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G Moreno et al.
Archives of biochemistry and biophysics, 386(2), 243-250 (2001-05-23)
We have examined whether the effects of singlet oxygen (1O2) produced by photodynamic action on the mitochondrial permeability transition (PT) can be modulated by the localization of photosensitizers in irradiated mitochondria. We have previously shown that oxidation due to 1O2
F Agani et al.
Molecular pharmacology, 54(5), 749-754 (1998-11-06)
In response to hypoxia, mammalian cells express multiple gene products [including erythropoietin (EPO) and vascular endothelial growth factor (VEGF)] that serve to increase O2 delivery, as well as glucose transporters and glycolytic enzymes (such as enolase 1) that allow metabolic
B Roberg et al.
Neurochemical research, 24(3), 383-390 (1999-04-24)
Glutamine transport into rat brain mitochondria (synaptic and non-synaptic) was monitored by the uptake of [3H]glutamine as well as by mitochondrial swelling. The uptake is inversely correlated to medium osmolarity, temperature-dependent, saturable and inhibited by mersalyl, and glutamine is upconcentrated
Georgiy A Belogurov et al.
The Journal of biological chemistry, 277(25), 22209-22214 (2002-04-17)
H(+)-translocating pyrophosphatase (H(+)-PPase) of the photosynthetic bacterium Rhodospirillum rubrum was expressed in Escherichia coli C43(DE3) cells. Recombinant H(+)-PPase was observed in inner membrane vesicles, where it catalyzed both PP(i) hydrolysis coupled with H(+) transport into the vesicles and PP(i) synthesis.
Jason M Gooding et al.
European journal of biochemistry, 271(5), 954-961 (2004-03-11)
Recent studies have suggested that parts of the hepatic activities of diacylglycerol acyltransferase and acyl cholesterol acyltransferase are expressed in the lumen of the endoplasmic reticulum (ER). However the ER membrane is impermeable to the long-chain fatty acyl-CoA substrates of
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