330678

SM ELISA (Clear)

Avanti Research^™ - A Croda Brand

• Synonym(s): SM ELISA, Brain Sphingomyelin ELISA Snoopers^™, Clear, for use in absorbance applications
• UNSPSC Code: 41116158
• NACRES: NA.84

Properties

• form: liquid
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• packaging: 1 ea of 1 × (ELISA strip packaged in foil pouch)
• shipped in: wet ice
• storage temp.: 2-8°C

Description

General description

Avanti Lipid Snoopers^™ are lipid microarrays useful in semi-quantitative measurements. These snoopers are relatively stable and provide a higher sensitivity compared to the conventional enzyme-linked immunosorbent assay (ELISA) methods. Sphingomyelin (SM) is a sphingolipid present in central nervous system as a component of the myelin sheath and neuronal cells. It is synthesized from ceramide in Golgi. Acid sphingomyelinase (aSMase) degrades SM.

ELISA Snoopers^™ are 8-well strips pre-coated with a single high-quality lipid species. They can be used to investigate protein-lipid interactions, and characterize and titrate lipid binding proteins. This format provides the following advantages:

• quantitative lipid-protein binding studies
• assemble a 96-well plate using only the lipids of interest for binding studies
• flexibility - use 8 to 96 wells, and 1 to 12 lipids as needed.

The 8-well strips are available in optically clear, white, or black surfaces for use in colormetric, luminescent and fluorescent assays, respectively. Avanti Lipid Snoopers ELISA Strips allow multiple sample conditions to be probed simultaneously in a single plate making them a perfect complement to Avanti Lipid Snoopers Nitrocellulose Strips.

Biochem/physiol Actions

Sphingomyelin (SM) participates in the inflammatory process and signalling pathways. It is a crucial regulator for myelin integrity, axon maturation, cognition and brain development. The SM to ceramide ratio is crucial, as high ceremide levels are implicated in depression. Altered levels of sphingomyelin due to sphingomyelinase deficiency results in Niemann–Pick disease.

Packaging

ELISA Strip Packaged in Foil Pouch (330678-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Snoopers is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): No data available
• Flash Point(C): No data available