L070150

Fast Deprotection Cap 2

45-55 g/L (TAC2O content, gravimetric)

• Synonym(s): Fast Deprotection Cap A
• UNSPSC Code: 12352106
• NACRES: NA.21

Properties

• type: for DNA synthesis; for DNA synthesis
• product line: Proligo Reagents
• form: liquid
• storage condition: dry at room temperature
• concentration: 45-55 g/L (TAC2O content, gravimetric)
• technique(s): DNA synthesis: suitable
• color: clear
• storage temp.: room temp

Description

General description

Fast Deprotection Cap 2 is an acetonitrile-based liquid reagent. It has a composition of Acetonitrile / TAC2O 100/5 (v/w).

Preparation Note

Acetonitrile / TAC₂O 100/5 (v/w)

Other Notes

Fast Deprotection Cap A solution must be used for synthesis with Sigma-Aldrich′s TAC-protected phosphoramidites. Fast Deprotection Cap A solution, containing tert-butylphenoxyacetyl acetic anhydride (TAC₂O) in acetonitrile, is used in place of Cap A solution to ensure that the displacement of tert-butylphenoxyacetyl (TAC) on guanine bases of the TAC-protected DNA and RNA phosphoramidites does not occur.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302 + H312 + H332,H319
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 35.6 °F - (Acetonitrile)
• Flash Point(C): 2.0 °C - (Acetonitrile)