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931853

Sigma-Aldrich

SPhos Pd G6 acylation

≥95%

Synonym(s):

(SPhos)Pd(4-CH2CH2CONHSPh)Br

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About This Item

Empirical Formula (Hill Notation):
C39H47BrNO6PPd
CAS Number:
Molecular Weight:
843.09
UNSPSC Code:
12352100
NACRES:
NA.21

Quality Level

Assay

≥95%

form

powder

reaction suitability

reagent type: catalyst
reaction type: Cross Couplings

Application

SPhos Pd G6 acylation is an oxidative addition complex (OAC) of SPhos for use in bioconjugation. The pendant NHS-functional group allows coupling to protein amines through a selective acylation. The protein-OAC can then be reacted with a second, cysteine-containing protein. This facile approach allows for protein homodimerization as well as the formation of antibody-protein conjugates.

Learn more about G6 Buchwald precatalysts

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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