92748

4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate

≥97.0%, for peptide synthesis

• Synonym(s): 2-(Trimethylsilyl)ethyl 4-nitrophenyl carbonate, TEOC-ONp
• Empirical Formula (Hill Notation): C₁₂H₁₇NO₅Si
• CAS Number: 80149-80-0
• Molecular Weight: 283.35
• Beilstein: 4320585
• EC Number: 279-406-7
• MDL number: MFCD00042930
• UNSPSC Code: 12352108
• PubChem Substance ID: 57653487
• NACRES: NA.22

Properties

• product name: 4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate, ≥97.0%
• Quality Level: 100
• Assay: ≥97.0%
• form: crystals
• mp: 35-40 °C
• application(s): peptide synthesis
• storage temp.: 2-8°C
• SMILES string: C[Si](C)(C)CCOC(=O)Oc1ccc(cc1)[N+]([O-])=O
• InChI: 1S/C12H17NO5Si/c1-19(2,3)9-8-17-12(14)18-11-6-4-10(5-7-11)13(15)16/h4-7H,8-9H2,1-3H3
• InChI key: ZAQWGGKIMQIVGM-UHFFFAOYSA-N

Description

Application

4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate can be used as:

• A protecting group for an amine in one of the key synthetic steps of kottamide E total synthesis.
• A starting material to prepare a cis-butene derivative, which is used as a polymer terminating agent in the synthesis of monotelechelic glycopolymers.

Other Notes

Reagent for the introduction of the TEOC-amino protecting group which can be cleaved by F^-

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves