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767344

Sigma-Aldrich

Poly(D,L-lactide)

average Mn 20,000 (NMR), PDI ≤1.3

Synonym(s):

PDLA, PLA, polyDL-lactide

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About This Item

UNSPSC Code:
12162002
NACRES:
NA.23

form

crystals

mol wt

average Mn 20,000 (NMR)

degradation timeframe

<6 months

mp

320-350 °C

PDI

≤1.3

storage temp.

2-8°C

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Related Categories

Application

Used in Drug Delivery including coating nanoparticles. Can be end-group functionalizated or used as a macroinitiator/block precursor.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Synthesis of Shape Amphiphiles Based on Functional Polyhedral Oligomeric Silsesquioxane End-Capped Poly(L-Lactide) with Diverse Head Surface Chemistry
Zhang W B, et al.
Macromolecules, 44(8), 2589-2596 (2011)
Poly(lactide)-block-Poly(HEMA) Block Copolymers: An Orthogonal One-Pot Combination of ROP and ATRP, Using a Bifunctional Initiator
Wolf F F, et al.
Macromolecules, 42(15), 5622-5628 (2009)
Preparation of Protein-Loaded Poly(L-Lactide) Microspheres by Solution-Enhanced Dispersion by Supercritical CO2
Chen A Z, et al.
Journal of Biomimetics, Biomaterials, and Tissue Engineering, 11, 93-100 (2011)

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Biodegradable Polyester Based Nanoparticle Formation by Miniemulsion Technique

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

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