746193

Maleimide-PEG₆-succinimidyl ester

• Synonym(s): 25-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-23-oxo-4,7,10,13,16,19-hexaoxa-22-azapentacosanoic acid 2,5-dioxo-1-pyrrolidinyl ester, Maleimide-PEG₆-NHS ester
• Empirical Formula (Hill Notation): C₂₆H₃₉N₃O₁₃
• CAS Number: 1137109-21-7
• Molecular Weight: 601.60
• MDL number: MFCD11041093
• UNSPSC Code: 12352108
• PubChem Substance ID: 329765747
• NACRES: NA.22

Properties

• form: liquid
• reaction suitability: reaction type: Pegylations; reagent type: cross-linking reagent
• functional group: NHS ester; maleimide
• storage temp.: −20°C
• SMILES string: O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O
• InChI: 1S/C26H39N3O13/c30-21(5-8-28-22(31)1-2-23(28)32)27-7-10-37-12-14-39-16-18-41-20-19-40-17-15-38-13-11-36-9-6-26(35)42-29-24(33)3-4-25(29)34/h1-2H,3-20H2,(H,27,30)
• InChI key: AVCPTIUOZBWCKE-UHFFFAOYSA-N

Description

Application

Heterobifunctional crosslinker with an ethylene oxide spacer for linking amine- to sulfhydryl-containing compounds or biomolecules. Maleimide functional group will react with sulfhydryls and the succinimidyl ester group will react with amines. Spacer length is 31.7 angstroms.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable