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Key Documents

726168

Sigma-Aldrich

Methoxypolyethylene glycol azide

PEG average Mn 10,000

Synonym(s):

Polyethylene glycol, α-Methoxy-ω-azido-PEG, O-(2-Azidoethyl)-O′-methylpolyethylene glycol, PEG-Azide, mPEG Azide

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About This Item

Linear Formula:
N3CH2CH2(OCH2CH2)nOCH3
CAS Number:
UNSPSC Code:
12162002
NACRES:
NA.22

form

lumps

Quality Level

mol wt

PEG average Mn 10,000

Ω-end

azide

α-end

methoxy

storage temp.

−20°C

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Related Categories

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Articles

Circulatory half-life is a key success factor for new drugs. In this respect, PEGylation or PEG-ing—the modification of potential candidates ranging from non-peptidic small molecules to peptides and proteins, antibody fragments, aptamers, and saccharides or oligonucleotides with polyethylene glycol chains—offers numerous advantages.

Professor Randal Lee (University of Houston, USA) discusses design considerations for iron oxide magnetic nanospheres and nanocubes used for biosensing, including synthetic procedures, size, and shape. The effects of these variables are discussed for various volumetric-based and surface-based detection schemes.

Kanjiro Miyata (The University of Tokyo, Japan) provides insights on the rational design of polymeric materials for “smart” oligonucleotide delivery.

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