Copper-mediated trifluoromethylthiolation of α-diazoesters.

Copper-mediated trifluoromethylthiolation of α-diazoesters.

Organic letters (2014-03-26)

Mingyou Hu, Jian Rong, Wenjun Miao, Chuanfa Ni, Yongxin Han, Jinbo Hu

ABSTRACT

A novel Cu-mediated trifluoromethylthiolation of diazo compounds has been developed that provides a convenient synthetic route for the efficient α-trifluoromethylthiolation of simple esters under mild reaction conditions. The reaction is typically carried out at room temperature, and water could be used to promote the reaction.

MATERIALI

N° Catalogo

Marchio

Descrizione del prodotto

270555

Sigma-Aldrich

N,N-dimetilacetammide, suitable for HPLC, ≥99.9%

38840

Sigma-Aldrich

N,N-dimetilacetammide, puriss. p.a., ≥99.5% (GC)

185884

Sigma-Aldrich