Passa al contenuto
Merck

One-pot synthesis of benzofurans via palladium-catalyzed enolate arylation with o-bromophenols.

Organic letters (2008-08-30)
Christian Eidamshaus, Jason D Burch
ABSTRACT

A one-pot synthesis of benzofurans which utilizes a palladium-catalyzed enolate arylation is described. The process demonstrates broad substrate scope and provides differentially substituted benzofurans in moderate to excellent yields. The utility of the method is further demonstrated by the synthesis of the natural product eupomatenoid 6 in three steps.

MATERIALI
N° Catalogo
Marchio
Descrizione del prodotto

Sigma-Aldrich
2-Bromophenol, 98%