Passa al contenuto
Merck

Studying Kinetochore Kinases.

Methods in molecular biology (Clifton, N.J.) (2016-05-20)
Adrian T Saurin, Geert J P L Kops
ABSTRACT

Mitotic kinetochores are signaling network hubs that regulate chromosome movements, attachment error-correction, and the spindle assembly checkpoint. Key switches in these networks are kinases and phosphatases that enable rapid responses to changing conditions. Describing the mechanisms and dynamics of their localized activation and deactivation is therefore instrumental for understanding the spatiotemporal control of chromosome segregation.

MATERIALI
N° Catalogo
Marchio
Descrizione del prodotto

Sigma-Aldrich
Anticorpo anti-fosfo-istone H3 (Ser10) marcatore di mitosi, Upstate®, from rabbit
Sigma-Aldrich
Anti-Mps1 Antibody, NT, clone 3-472-1, clone 3-472-1, Upstate®, from mouse
Sigma-Aldrich
Anti-Mad1 Antibody, clone BB3-8, clone BB3-8, from mouse