- Induction of pH sensitivity on the fluorescence lifetime of quantum dots by NIR fluorescent dyes.
Induction of pH sensitivity on the fluorescence lifetime of quantum dots by NIR fluorescent dyes.
Journal of the American Chemical Society (2012-03-01)
Rui Tang, Hyeran Lee, Samuel Achilefu
PMID22360301
ABSTRACT
Modulation of the fluorescence lifetime (FLT) of CdTeSe/ZnS quantum dots (QDs) by near-IR (NIR) organic chromophores represents a new strategy for generating reproducible pH-sensing nanomaterials. The hybrid construct transfers the pH sensitivity of photolabile NIR cyanine dyes to highly emissive and long-lifetime pH-insensitive QDs, thereby inducing a reproducible FLT change from 29 ns at pH >7 to 12 ns at pH <5. This approach provides an unparalleled large dynamic FLT range for pH sensing at NIR wavelengths.
MATERIALI