R2027

Ral B human

recombinant, expressed in E. coli, buffered aqueous glycerol solution

• Numero MDL: MFCD03792555
• Codice UNSPSC: 12352202
• NACRES: NA.56

Proprietà

• Ricombinante: expressed in E. coli
• Livello qualitativo: 200
• Forma fisica: buffered aqueous glycerol solution
• N° accesso UniProt: P11234
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... RALB(5899)

Descrizione

Applicazioni

Can be used as a control in immunoblotting and in protein binding assays.

Azioni biochim/fisiol

Ral B (21 kDa, native), a member of the Ras-like GTP binding protein family, is a crucial link in intracellular signaling cascades.

Ral B has been implicated in invasion and metastasis of human cancer cells. Reports have shown that depletion of Ral B by siRNA results in significantly reduced migration rates of tumor cells, while constitutively active Ral B promoted migration.

Altre note

GST-tagged Ras-like fusion protein

Stato fisico

Supplied as a solution in 50 mM Tris, pH 7.5, containing 150 mM sodium chloride, 10 mM magnesium chloride, 1 mM DTT, and 10% glycerol.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids