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Merck
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D9302

Sigma-Aldrich

Diacerein

≥95% (HPLC)

Sinonimo/i:

1,8-Diacetoxy-3-carboxyanthraquinone

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About This Item

Formula empirica (notazione di Hill):
C19H12O8
Numero CAS:
13739-02-1
Peso molecolare:
368.29
Numero CE:
237-310-2
Numero MDL:
MFCD00468030
Codice UNSPSC:
41116107
ID PubChem:
24894281
NACRES:
NA.25

Saggio

≥95% (HPLC)

Forma fisica

powder

Stringa SMILE

CC(=O)Oc1cccc2C(=O)c3cc(cc(OC(C)=O)c3C(=O)c12)C(O)=O

InChI

1S/C19H12O8/c1-8(20)26-13-5-3-4-11-15(13)18(23)16-12(17(11)22)6-10(19(24)25)7-14(16)27-9(2)21/h3-7H,1-2H3,(H,24,25)
TYNLGDBUJLVSMA-UHFFFAOYSA-N

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Azioni biochim/fisiol

Diacerin is an inhibitor of Interleukin-1B (IL-1B) production.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

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Umut Kalyoncu et al.
Joint, bone, spine : revue du rhumatisme, 76(4), 389-393 (2009-02-17)
The objective of the present study was to assess the frequency of self-reported psoriasis in a hip osteoarthritis (OA) cohort, and a secondary objective was to assess the course of hip OA with psoriasis. ECHODIAH was a 3-year, randomised double-blind
Pascal Richette
La Revue du praticien, 62(5), 654-660 (2012-06-27)
According to the European League of Associations of Rheumatology (EULAR) and the American College of Rheumatology (ACR), acetaminophen should be used as a first-line therapy in patients with osteoarthritis, because of its safety and effectiveness. NSAID should be considered in
Wanwisa Suwannaloet et al.
TheScientificWorldJournal, 2012, 310745-310745 (2012-06-06)
The osteochondral healing potential of hyaluronic acid (HA) plus diacerein was evaluated in subchondral-drilling- (SCD-) induced fibrocartilage generation in rabbits. A full-thickness chondral defect was created along the patellar groove of both knees and then SCD was subsequently performed only
Maria G Ramos-Zavala et al.
Diabetes care, 34(7), 1591-1594 (2011-05-26)
To assess the effect of diacerein on insulin secretion and metabolic control in drug-naïve patients with type 2 diabetes. A randomized, double-blind, placebo-controlled clinical trial was carried out in 40 drug-naïve adult patients with type 2 diabetes. A metabolic profile
Ren-Yeong Huang et al.
Medical hypotheses, 79(2), 165-167 (2012-05-16)
Periodontal diseases are chronic inflammatory diseases characterized by the destruction of the tooth-supporting structures. They are the most prevalent form of bone pathology in humans and act as a modifying factor of the systemic health of patients. Accumulating evidence has
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