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Key Documents

329M-9

Sigma-Aldrich

Renal Cell Carcinoma (PN-15) Mouse Monoclonal Antibody

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About This Item

Codice UNSPSC:
12352200
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

culture supernatant

Tipo di anticorpo

primary antibodies

Clone

PN-15, monoclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forma fisica

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (329M-94)
vial of 0.5 mL concentrate (329M-95)
bottle of 1.0 mL predilute (329M-97)
vial of 1.0 mL concentrate (329M-96)
bottle of 7.0 mL predilute (329M-98)

Produttore/marchio commerciale

Cell Marque

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

Isotipo

IgG1κ

Controllo

renal cell carcinoma

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

cytoplasmic, membranous

Descrizione generale

Anti-renal cell carcinoma (RCC) recognizes a 200 kD glycoprotein localized in the brush border of the proximal renal tubule. This antibody immunoreacts with approximately 90% of primary renal cell carcinomas and approximately 85% of metastatic renal cell carcinomas. Other tumors that may react with this antibody are parathyroid adenoma and an occasional breast carcinoma. Nephroblastoma, oncocytoma, mesoblasticnephroma, transitional cell carcinoma, and angiomyolipoma are not labeled with this antibody.
Anti-renal cell carcinoma (RCC) recognizes a 200 kD glycoprotein localized in the brush border of the proximal renal tubule. This antibody immunoreacts with most primary renal cell carcinomas and can aid in the diagnosis when renal cell carcinoma enters the differential diagnosis.

Qualità


IVD

IVD

IVD

RUO

Linkage

Renal Cell Carcinoma Positive Control Slides, Product No. 329S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Neriman Gokden et al.
Applied immunohistochemistry & molecular morphology : AIMM, 11(2), 116-119 (2003-06-05)
Renal cell carcinoma (RCC) not uncommonly presents with metastases and causes diagnostic difficulty to the cytopathologist who is involved in the initial diagnostic workup of tumors with an unknown primary site. RCC marker (RCC Ma) recognizes a human proximal tubule
A K Avery et al.
The American journal of surgical pathology, 24(2), 203-210 (2000-02-19)
The majority of renal neoplasms can be distinguished on the basis of histologic examination alone; however, there are morphologic similarities between clear cell renal carcinoma and chromophobe cell carcinoma, as well as between the granular/eosinophilic variants of these tumors and
D K McGregor et al.
The American journal of surgical pathology, 25(12), 1485-1492 (2001-11-22)
The diagnosis of primary or metastatic renal cell carcinoma (RCC) can be difficult, especially in small biopsies, because of the wide variety of histologic appearances and clinical presentations that RCC can assume. An immunomarker specific for RCC is currently not

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