27885

Coumestrol

≥95.0% (HPLC)

• Sinonimo/i: 7,12-Dihydroxycoumestan
• Formula empirica (notazione di Hill): C₁₅H₈O₅
• Numero CAS: 479-13-0
• Peso molecolare: 268.22
• Beilstein: 266702
• Numero CE: 207-525-6
• Numero MDL: MFCD00016885
• Codice UNSPSC: 41116107
• ID PubChem: 57648279
• NACRES: NA.77

Proprietà

• Saggio: ≥95.0% (HPLC)
• Forma fisica: powder
• Impurezze: ≤10.0% water
• Punto di fusione: ≥350 °C (lit.)
• Stringa SMILE: Oc1ccc-2c(OC(=O)c3c-2oc4cc(O)ccc34)c1
• InChI: 1S/C15H8O5/c16-7-1-3-9-11(5-7)19-14-10-4-2-8(17)6-12(10)20-15(18)13(9)14/h1-6,16-17H; ZZIALNLLNHEQPJ-UHFFFAOYSA-N
• Informazioni sul gene: human ... ESR1(2099) , ESR2(2100) ; mouse ... Esr1(13982) ; rat ... Ar(24208)

Descrizione

Applicazioni

• Phytoestrogens in Fish Feed Production:Coumestrolis is used as a biomarkers in fish feed production, facilitating the assessment of plant raw materials used in these feeds (Pavlopoulos et al., 2023).


• Coumestrol and Soybean Leaf Senescence: Coumestrol′s role in soybean leaf senescence is explored, particularly its interactions with phytohormones, suggesting potential agronomic benefits and applications in crop science, it acts as a phytoalexin (Mun et al., 2021).


• Systemic Defense in Soybeans: Investigating the effects of priming with coumestrol on soybean defense against the root-lesion nematode, this research highlights its potential as a natural plant defense enhancer (Adss et al., 2021).

Azioni biochim/fisiol

Coumestrol has anti-estrogenic actions in the brain and pituitary, mediated through estrogen receptor-α.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302,H315,H319,H335
• Consigli di prudenza: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves