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Merck

WNT3

wingless-type MMTV integration site family, member 3

Sinonimi:
INT4
Specie:
ID UniProtKB:
ID gene:
  • Human(7473) Summary: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008]
  • Mouse(22415) wingless-related MMTV integration site 3
  • Rat(24882) wingless-type MMTV integration site family, member 3
  • Zebrafish(569420) wingless-type MMTV integration site family, member 3
  • Horse(100049880) wingless-type MMTV integration site family, member 3
  • domestic cat(101088533) wingless-type MMTV integration site family, member 3
  • dog(609107) wingless-type MMTV integration site family, member 3
  • chicken(374142) wingless-type MMTV integration site family, member 3
  • domestic guinea pig(100734613) wingless-type MMTV integration site family, member 3
  • Domestic Rabbit(100009033) wingless-type MMTV integration site family, member 3
  • naked mole-rat(101724651) wingless-type MMTV integration site family, member 3
  • cow(540753) wingless-type MMTV integration site family, member 3
  • sheep(101120096) wingless-type MMTV integration site family, member 3

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-WNT3 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Applicazione
western blot
Anti-Wnt3 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human WNT3,
Specie
human