STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
Sinonimi:
D12S1644, IL-4-STAT, STAT6B, STAT6C
Specie:
Human STAT6 (6778), Mouse Stat6 (20852), Rat Stat6 (362896), Zebrafish stat6 (337413), Horse STAT6 (100050053), domestic cat STAT6 (101089873), dog STAT6 (100142679), chicken STAT6 (100859196), cow STAT6 (353105), sheep STAT6 (101102134) ...Più
ID UniProtKB:
ID gene:
- Human(6778) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
- Mouse(20852) signal transducer and activator of transcription 6
- Rat(362896) signal transducer and activator of transcription 6, interleukin-4 induced
- Zebrafish(337413) signal transducer and activator of transcription 6, interleukin-4 induced
- Horse(100050053) signal transducer and activator of transcription 6, interleukin-4 induced
- domestic cat(101089873) signal transducer and activator of transcription 6, interleukin-4 induced
- dog(100142679) signal transducer and activator of transcription 6, interleukin-4 induced
- chicken(100859196) signal transducer and activator of transcription 6, interleukin-4 induced
- cow(353105) signal transducer and activator of transcription 6, interleukin-4 induced
- sheep(101102134) signal transducer and activator of transcription 6, interleukin-4 induced
- naked mole-rat(101725744) signal transducer and activator of transcription 6, interleukin-4 induced
- Domestic Rabbit(100344264) signal transducer and activator of transcription 6, interleukin-4 induced
- domestic guinea pig(100726686) signal transducer and activator of transcription 6, interleukin-4 induced
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ELISA
N° Catalogo
Descrizione
Specie
Phosphotyrosine STAT6 / Signal Transducer and Activator of Transcription 6 ELISA Kit, ,
Specie
human
Cell-Based ELISA for detecting phospho-STAT6 (pTyr641) in cultured cell lines, 96 assays,
Specie
mouse, human
Cell-Based phospho-STAT ELISA Samper Kit for detecting phospho-STAT1 (pTyr701), phospho-STAT3 (pTyr705), and phospho-STAT5 (pTyr694) in cultured cell lines, 192 assays,
Specie
mouse, rat, human
Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-STAT6 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1, clone 19E2.1, from mouse,
Reattività con
human, mouse
Applicazione
flow cytometry
western blot
western blot
Anti-phospho-STAT6 (Tyr641) Antibody, clone 16E12, clone 16E12, Upstate®, from mouse,
Reattività con
human, mouse, rat
Applicazione
western blot
Anti-phospho-STAT6 (pTyr641) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
western blot
western blot
Anti-STAT6 Antibody, clone 1C13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, monkey
Applicazione
affinity binding assay
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Proteins
N° Catalogo
Descrizione
Specie
STAT6, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human