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Merck

SMOX

spermine oxidase

Sinonimi:
C20orf16, PAO, PAO-1, PAOH1, SMO
Specie:
ID UniProtKB:
ID gene:
  • Human(54498) Summary: Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism. [provided by RefSeq, Jul 2012]
  • Mouse(228608) spermine oxidase
  • Rat(308652) spermine oxidase
  • fruit fly(31738) Smad on X
  • Horse(100052311) spermine oxidase
  • domestic cat(101084867) spermine oxidase
  • dog(485787) spermine oxidase
  • chicken(422934) spermine oxidase
  • Zebrafish(387290) spermine oxidase
  • cow(527211) spermine oxidase
  • sheep(101118975) spermine oxidase
  • domestic guinea pig(100715262) spermine oxidase
  • Domestic Rabbit(100347645) spermine oxidase
  • naked mole-rat(101707899) spermine oxidase

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-SMOX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-SMOX antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-SMOX (151-165) antibody produced in rabbit, IgG fraction of antiserum,
Reattività con
human
Applicazione
western blot
Anti-SMOX (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reattività con
canine, human
Applicazione
western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Smox,
Specie
mouse
MISSION® esiRNA, targeting human SMOX,
Specie
human