RAD50
RAD50 homolog (S. cerevisiae)
Sinonimi:
NBSLD, RAD502, hRad50
Specie:
Human RAD50 (10111), Mouse Rad50 (19360), Rat Rad50 (64012), fruit fly rad50 (37564), Thale Cress RAD50 (817756), Horse RAD50 (100063198), domestic cat RAD50 (101095875), dog RAD50 (474674), chicken RAD50 (416329), Zebrafish rad50 (553029) ...Più
ID UniProtKB:
ID gene:
- Human(10111) Summary: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010]
- Mouse(19360) RAD50 homolog (S. cerevisiae)
- Rat(64012) RAD50 homolog (S. cerevisiae)
- fruit fly(37564) CG6339 gene product from transcript CG6339-RE
- Thale Cress(817756) DNA repair protein RAD50
- Horse(100063198) RAD50 homolog (S. cerevisiae)
- domestic cat(101095875) RAD50 homolog (S. cerevisiae)
- dog(474674) RAD50 homolog (S. cerevisiae)
- chicken(416329) RAD50 homolog (S. cerevisiae)
- Zebrafish(553029) RAD50 homolog (S. cerevisiae)
- domestic guinea pig(100719847) RAD50 homolog (S. cerevisiae)
- naked mole-rat(101719180) RAD50 homolog (S. cerevisiae)
- Domestic Rabbit(100328725) RAD50 homolog (S. cerevisiae)
- cow(788127) RAD50 homolog (S. cerevisiae)
- sheep(101123035) RAD50 homolog (S. cerevisiae)
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-RAD50 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
immunohistochemistry
Anticorpo anti-Rad50, clone 13B3/2C6, clone 13B3/2C6, Upstate®, from mouse,
Reattività con
human, mouse
Applicazione
immunoprecipitation (IP)
western blot
western blot
Anti-RAD50 Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human, mouse, rat
Applicazione
immunocytochemistry
western blot
western blot