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Merck

PTPRS

protein tyrosine phosphatase, receptor type, S

Sinonimi:
PTPSIGMA
Specie:
ID UniProtKB:
ID gene:
  • Human(5802) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(19280) protein tyrosine phosphatase, receptor type, S
  • Rat(25529) protein tyrosine phosphatase, receptor type, S
  • naked mole-rat(101715786) protein tyrosine phosphatase, receptor type, S
  • cow(537480) protein tyrosine phosphatase, receptor type, S
  • sheep(101112817) protein tyrosine phosphatase, receptor type, S
  • chicken(396375) protein tyrosine phosphatase, receptor type, S
  • dog(485030) protein tyrosine phosphatase, receptor type, S
  • Horse(100069183) protein tyrosine phosphatase, receptor type, S
  • domestic cat(101083913) protein tyrosine phosphatase, receptor type, S

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-PTPRS Antibody, Clone 9H3.1, clone 9H3.1, from mouse,
Reattività con
human
Applicazione
immunohistochemistry
western blot

Proteins

N° Catalogo
Descrizione
Specie
PTPsigma/PTPRS Active human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Ptprs,
Specie
mouse