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Merck

PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

Sinonimi:
PAK5
Specie:
ID UniProtKB:
ID gene:
  • Human(56924) Summary: This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
  • Mouse(214230) p21 protein (Cdc42/Rac)-activated kinase 6
  • Rat(296078) p21 protein (Cdc42/Rac)-activated kinase 6
  • chicken(428837) p21 protein (Cdc42/Rac)-activated kinase 6
  • dog(487490) p21 protein (Cdc42/Rac)-activated kinase 6
  • domestic cat(101091201) p21 protein (Cdc42/Rac)-activated kinase 6
  • cow(539224) p21 protein (Cdc42/Rac)-activated kinase 6
  • Horse(100071463) p21 protein (Cdc42/Rac)-activated kinase 6
  • Goat(100860973) p21 protein (Cdc42/Rac)-activated kinase 6
  • sheep(101112573) p21 protein (Cdc42/Rac)-activated kinase 6
  • Domestic Rabbit(100348921) p21 protein (Cdc42/Rac)-activated kinase 6
  • naked mole-rat(101706200) p21 protein (Cdc42/Rac)-activated kinase 6
  • domestic guinea pig(100713585) p21 protein (Cdc42/Rac)-activated kinase 6

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-PAK6 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit
Applicazione
western blot
Anti-phospho-PAK5/6 (pSer602/560) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
Anti-Phospho-PAK4/PAK5/PAK6-S474/S560/S602 antibody produced in rabbit, ,
Reattività con
human, mouse
Applicazione
western blot
Anti-phospho-PAK5/6 (pSer602/Ser560) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse
Applicazione
western blot

Proteins

N° Catalogo
Descrizione
Specie
PAK6, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human PAK6, BUB1B-PAK6,
Specie
human