MAP2K6
mitogen-activated protein kinase kinase 6
Sinonimi:
MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3
Specie:
Human MAP2K6 (5608), Mouse Map2k6 (26399), Rat Map2k6 (114495), domestic guinea pig Map2k6 (100731419), naked mole-rat Map2k6 (101703028), Domestic Rabbit MAP2K6 (100355230), sheep MAP2K6 (101115047), Zebrafish map2k6 (65239), cow MAP2K6 (286883), Horse MAP2K6 (100053056) ...Più
ID UniProtKB:
ID gene:
- Human(5608) Summary: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008]
- Mouse(26399) mitogen-activated protein kinase kinase 6
- Rat(114495) mitogen-activated protein kinase kinase 6
- domestic guinea pig(100731419) mitogen-activated protein kinase kinase 6
- naked mole-rat(101703028) mitogen-activated protein kinase kinase 6
- Domestic Rabbit(100355230) mitogen-activated protein kinase kinase 6
- sheep(101115047) mitogen-activated protein kinase kinase 6
- Zebrafish(65239) mitogen-activated protein kinase kinase 6
- cow(286883) mitogen-activated protein kinase kinase 6
- Horse(100053056) mitogen-activated protein kinase kinase 6
- domestic cat(101089813) mitogen-activated protein kinase kinase 6
- chicken(417445) mitogen-activated protein kinase kinase 6
- dog(480454) mitogen-activated protein kinase kinase 6
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-MAP2K6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-MAP2K6 antibody produced in mouse, clone 2F2, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Anti-MKK6 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MAP2K6 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
western blot
Small Molecule - Inhibitor
N° Catalogo
Descrizione
Specie
Proteins
N° Catalogo
Descrizione
Specie
MKK6 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE),
Specie
human
MKK6/SKK3, active human, ≥80% (SDS-PAGE), recombinant, expressed in E. coli, Maltose binding protein tagged, buffered aqueous solution,
Specie
human
MKK6/SKK3 Protein, inactive, 50 g, Unactive, recombinant human MKK6, amino acids 4-end, fused at the N-terminus to a Mal-E tag, for use in Kinase Assays.,
Specie
human