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Merck

KDR

kinase insert domain receptor (a type III receptor tyrosine kinase)

Sinonimi:
CD309, FLK1, VEGFR, VEGFR2
Specie:
ID UniProtKB:
ID gene:
  • Human(3791) Summary: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
  • Mouse(16542) kinase insert domain protein receptor
  • Rat(25589) kinase insert domain receptor
  • Goat(100860836) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • sheep(443087) vascular endothelial growth factor receptor-2
  • Domestic Rabbit(100008607) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • domestic guinea pig(100726761) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • naked mole-rat(101726029) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Zebrafish(554230) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • cow(407170) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Horse(100033959) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • domestic cat(101090260) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • dog(482154) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • chicken(395323) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Thale Cress(839585) basic helix-loop-helix protein KIDARI

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ELISA

N° Catalogo
Descrizione
Specie
Human VEGF R2 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Specie
human
Mouse Kdr / Vascular Endothelial Growth Factor Receptor 2 ELISA Kit, ,
Specie
mouse

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-KDR/Flk-1/VEGFR2 Antibody, clone CH-11, clone CH-11, Upstate®, from mouse,
Reattività con
human, mouse
Applicazione
ELISA
immunocytochemistry

western blot
Anti-VEGFR2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse
Applicazione
ELISA
immunohistochemistry

western blot
Anti-phospho-VEGFR2 (pTyr1175) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

western blot
Anti-phospho-VEGFR2 (pTyr1214) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

western blot
Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-2 (KDR) antibody produced in mouse, clone 260.4, KDR-2, ascites fluid,
Reattività con
human
Applicazione
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Specie
human
SU 5416, ≥98% (HPLC),
Specie
human, mouse
Pazopanib, ,
Specie
human
α-Sexithiophene, ,
Specie
human, rat

Proteins

N° Catalogo
Descrizione
Specie
KDR Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant, human KDR amino acids 790-end,
for use in Kinase Assays.
,
Specie
human
VEGF Receptor-2 (Flk-1, KDR)/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human KDR,
Specie
human
MISSION® esiRNA, targeting mouse Kdr,
Specie
mouse