GSTM5
glutathione S-transferase mu 5
Sinonimi:
GSTM5-5, GTM5
Specie:
ID UniProtKB:
ID gene:
- Human(2949) Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. [provided by RefSeq, Jul 2008]
- Mouse(14866) glutathione S-transferase, mu 5
- Rat(64352) glutathione S-transferase, mu 5
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-GSTM5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Monoclonal Anti-GSTM5 antibody produced in mouse, clone 1G4, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
Monoclonal Anti-GSTM5, (C-terminal) antibody produced in mouse, clone 1B3, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
Anti-GSTM5 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
western blot
Cell Lines
N° Catalogo
Descrizione
Specie