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Merck

DDR1

discoidin domain receptor tyrosine kinase 1

Sinonimi:
CAK, CD167, DDR, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE
Specie:
ID UniProtKB:
ID gene:
  • Human(780) Summary: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
  • Mouse(12305) discoidin domain receptor family, member 1
  • Rat(25678) discoidin domain receptor tyrosine kinase 1
  • Zebrafish(100007346) discoidin domain receptor family, member 1
  • cow(534092) discoidin domain receptor tyrosine kinase 1
  • Horse(100050861) discoidin domain receptor tyrosine kinase 1
  • domestic cat(101096728) discoidin domain receptor tyrosine kinase 1
  • dog(474832) discoidin domain receptor tyrosine kinase 1
  • domestic guinea pig(100725492) discoidin domain receptor tyrosine kinase 1
  • naked mole-rat(101699683) discoidin domain receptor tyrosine kinase 1
  • sheep(101104279) discoidin domain receptor tyrosine kinase 1

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ELISA

N° Catalogo
Descrizione
Specie
Human DDR1 ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-phospho-DDR1 (pTyr513) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

western blot
Anti-Phospho-DDR1-Y792 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
western blot
Anti-CD167a/DDR1 Antibody, clone 5D5, clone 5D5, from mouse,
Reattività con
human
Applicazione
flow cytometry
immunocytochemistry
Anti-CD167a/DDR1 Antibody, clone 1D11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
bovine, human, monkey, mouse, porcine, rat
Applicazione
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-DDR1 (AB1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
bovine, dog, horse, human, monkey, pig
Applicazione
immunohistochemistry

Proteins

N° Catalogo
Descrizione
Specie
DDR1 (444-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Ddr1,
Specie
mouse
MISSION® esiRNA, targeting human DDR1,
Specie
human