Passa al contenuto
Merck

CTNNB1

catenin (cadherin-associated protein), beta 1, 88kDa

Sinonimi:
CTNNB, MRD19, armadillo
Specie:
ID UniProtKB:
ID gene:
  • Human(1499) Summary: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009]
  • Mouse(12387) catenin (cadherin associated protein), beta 1
  • Rat(84353) catenin (cadherin associated protein), beta 1
  • naked mole-rat(101720578) catenin (cadherin-associated protein), beta 1, 88kDa
  • domestic guinea pig(100732604) catenin (cadherin-associated protein), beta 1, 88kDa
  • sheep(100294600) catenin (cadherin-associated protein), beta 1, 88kDa
  • Domestic Rabbit(100125985) catenin (cadherin-associated protein), beta 1, 88kDa
  • Zebrafish(30265) catenin (cadherin-associated protein), beta 1
  • chicken(395964) catenin (cadherin-associated protein), beta 1, 88kDa
  • cow(539003) catenin (cadherin-associated protein), beta 1, 88kDa
  • Horse(100055241) catenin (cadherin-associated protein), beta 1, 88kDa
  • domestic cat(101097342) catenin (cadherin-associated protein), beta 1, 88kDa
  • dog(477032) catenin (cadherin-associated protein), beta 1, 88kDa

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Monoclonal Anti-β-Catenin antibody produced in mouse, clone 15B8, ascites fluid,
Reattività con
bovine, canine, chicken, human
Applicazione
immunocytochemistry
immunofluorescence

immunohistochemistry

microarray

western blot
Anti-β-Catenin−Cy3 antibody, Mouse monoclonal, clone 15B8, purified from hybridoma cell culture,
Reattività con
bovine, canine, chicken, human
Applicazione
immunofluorescence
Monoclonal Anti-β-Catenin antibody produced in mouse, clone 6F9, ascites fluid,
Reattività con
bovine, canine, chicken, human
Applicazione
immunofluorescence
microarray

western blot
Anti-CTNNB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-CTNNB1 (Ab-33) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot

Cell Lines

N° Catalogo
Descrizione
Specie
A549 Cells GFP-CTNNB1 RFP-LMNB1, ,
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
Catenin β, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human CTNNB1,
Specie
human
MISSION® esiRNA, targeting mouse Ctnnb1,
Specie
mouse