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Merck

AKR1B1

aldo-keto reductase family 1, member B1 (aldose reductase)

Sinonimi:
ADR, ALDR1, ALR2, AR
Specie:
ID UniProtKB:
ID gene:
  • Human(231) Summary: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]
  • Rat(24192) aldo-keto reductase family 1, member B1 (aldose reductase)
  • Zebrafish(415138) aldo-keto reductase family 1, member B1 (aldose reductase)
  • cow(317748) aldo-keto reductase family 1, member B1 (aldose reductase)
  • domestic cat(101095406) aldo-keto reductase family 1, member B1 (aldose reductase)
  • dog(607537) aldo-keto reductase family 1, member B1 (aldose reductase)
  • sheep(101120824) aldo-keto reductase family 1, member B1 (aldose reductase)
  • Domestic Rabbit(100009122) aldo-keto reductase family 1, member B1 (aldose reductase)
  • domestic guinea pig(100718017) aldo-keto reductase family 1, member B1 (aldose reductase)
  • naked mole-rat(101720124) aldo-keto reductase family 1, member B1 (aldose reductase)

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-AKR1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-AKR1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
Anti-AKR1B1 antibody produced in rabbit, IgG fraction of antiserum,
Reattività con
dog, human, mouse, pig, rat
Applicazione
western blot
Anti-AKR1B1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
guinea pig, horse, human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-AKR1B1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Acido (±)-6-idrossi-2,5,7,8-tetrametilcromano-2-carbossilico, 97%,
Specie
rat
Hippuric acid, 98%,
Specie
rat
Fluorene-9-carboxylic acid, 96%,
Specie
rat
(±)-Gossypol from cotton seeds, ≥95% (HPLC),
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
Aldose Reductase human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human AKR1B1,
Specie
human