Passa al contenuto
Merck

The Power of Small

The Smallest, Automated, High-Throughput Bioreactor Yet

The pressure to reduce manufacturing costs is driving the need to improve process efficiency and flexibility, sparking further interest in perfusion technology. As with most processes, success is determined at the process development stage.

The Mobius® Breez Microbioreactor is a 2 mL automated, single-use, perfusion cell culture platform designed to support gentle, adaptable, and reproducible cell culture processes. The system is capable of accelerating a range of applications such as cell line development, media screening and optimization, and early process development.

We invite you to see the Mobius® Breez Microbioreactor in action. Your perfusion journey starts with a Demo! 

Request a Demo
The 2 mL microbioreactor cassette integrates automated pumps, valves, optical sensors, and a cell retention filter.

The 2 mL microbioreactor cassette integrates automated pumps, valves, optical sensors, and a cell retention filter.

A 2 mL Automated Perfusion Cell Culture Platform

  • Achieve high cell densities in a 2 mL perfusion process
  • Run more experiments in parallel for higher efficiency
  • Obtain high-quality perfusate on demand with reliable run-to-run performance
  • Reduce hands-on work with automated control and monitoring
  • Save on development time and costs through operational flexibility 
  • Focus on your goals with easy setup and installation
Mobius® Breez Microbioreactor equipped with 4 pneumatic optical digital (POD) controllers.

Mobius® Breez Microbioreactor

A Complete Platform for Perfusion

Perfusion is becoming a typical approach to achieving upstream process intensification. The ability to scale down these processes, however, has been limited due to a lack of appropriate technologies. The Mobius® Breez Microbioreactor is designed to meet the needs of full control at a small working volume with high-throughput capabilities. The system is comprised of a single-use, 2 mL microbioreactor consumable, four microbioreactor controllers, utility and communication hardware, and a laptop embedded with control software.

Predict Perfusion Performance at Smaller Scales

The Mobius® Breez Microbioreactor allows you to increase efficiency and reduce development timelines and costs over traditional technologies that require more material consumption. You can now achieve high cell densities with integrated pH, DO, temperature and cell density control via OD, and predict the performance of traditional stirred tank reactors at a much smaller volume scale, saving you media and associated costs.

Learn More
Related Products
Loading

Related Resources

Webinars

Slide 1 of 2
Scientist at a lab table

A Single-use, Scale down, Predictive Solution for Intensified Perfusion Development

The ability to scale down upstream intensified processes has been limited due to lack of appropriate technologies. This webinar describes a new 2mL single-use perfusion microbioreactor system that fulfills this throughput-performance gap.

Scientist at a lab table

Unleashing the Power of Perfusion: CHOZN® GS-/- Cell Line Development for Intensified Processes

Learn about the advantage of adopting a perfusion-specific CLD process to create more productive clones and find solutions for intensified processing using CHOZN® GS-/- cell line, a suite of best-in-class media, and Mobius® Breez Microbioreactor.

Related Integrated Offerings
Intensified and Continuous Upstream (USP) Processing
Make the best decisions to increase productivity, reduce costs, improve facility flexibility, and future-proof manufacturing strategies by intensifying your upstream process.
Real-Time Monitoring & Control in Biopharmaceuticals
Process Analytical Technology ensures biopharmaceutical quality by real-time process monitoring and control using analytical tools.
Bioprocessing Data Analytics Software
Our data management, visualization, and analytics software helps biotech companies to collect, aggregate, and analyze data, ultimately improving product quality and optimizing processes.
Bioprocessing Automation and Control Software
Our automation and control software platforms help reduce manual tasks and risks of errors, thereby increasing process reproducibility, product quality, and optimizing uptime.
Related Services
System Service Reliance Plans
Our system service reliance plans and maintenance services provide critical upkeep and repair of your bioprocessing systems, helping you to minimize risk, prevent downtime, and maintain optimum performance.
Custom Pre-GMP Cell Culture Media
Our imMEDIAte ADVANTAGE® service for pre-GMP, small scale custom media, feeds, supplements, and buffers provides the quick turn-around you need to complete your development work quicker – and accelerate your molecule to clinic sooner.
Custom GMP Cell Culture Products
Our custom cell culture product design experts can offer advice and support as you scale your bioprocess from clinical to commercial supply, assisting with liquid products, dry powder products, selection of raw materials, quality testing, flexible product packaging, and product documentation.
Related Product Categories
Bioprocessing Mobius® Single-Use Bioreactors
The Mobius® Bioreactor family includes the bench scale (2 mL and 3 L), pilot, clinical and commercial manufacturing (50 – 2,000 L) single-use bioreactors that enable cell culturing capabilities from early process development through commercial batch production.
Cell Retention
Enhance perfused seed train efficiency with our cell retention solution. Real-time monitoring and control.
Bioprocessing Cell Culture Media
Our off-the-shelf and customizable bioprocessing cell culture media (CCM) products enhance productivity in upstream mAb, vaccine, gene/cell therapy processes.
Bioprocessing Cell Lines
Our ready-to-use, off-the-shelf cell line systems greatly reduce the time, cost, and risk of developing new cell lines for production. Whether you are producing antibodies, recombinant proteins, or viral vectors for gene therapies, our cell line platforms can accelerate your upstream progress.

Request a Demo

Please use the form below if you want to evaluate Mobius® Breez Microbioreactor. Fields indicated with * are required.

Autenticati per continuare

Per continuare a leggere, autenticati o crea un account.

Non hai un Account?