PHL83522

Macelignan

phyproof^® Reference Substance

• Synonyme(s) : (+)-Anwulignan, 4-[(2S,3R)-4-(1,3-Benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxy-phenol, Anwulignan
• Formule empirique (notation de Hill): C₂₀H₂₄O₄
• Numéro CAS: 107534-93-0
• Poids moléculaire : 328.40
• Numéro MDL: MFCD09953803
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: primary reference standard
• Gamme de produits: phyproof^® Reference Substance
• Pureté: ≥98.0% (HPLC)
• Fabricant/nom de marque: PhytoLab
• Application(s): food and beverages
• Format: neat
• Chaîne SMILES: OC1=C(OC)C=C(C[C@H](C)[C@H](C)CC2=CC=C(OCO3)C3=C2)C=C1
• InChI: 1S/C20H24O4/c1-13(8-15-4-6-17(21)19(10-15)22-3)14(2)9-16-5-7-18-20(11-16)24-12-23-18/h4-7,10-11,13-14,21H,8-9,12H2,1-3H3/t13-,14+/m0/s1
• Clé InChI: QDDILOVMGWUNGD-UONOGXRCSA-N

Description

Description générale

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Actions biochimiques/physiologiques

Macelignan is a neuroprotective lingan isolated from nutmeg (Myristica fragrans) that protects dopaminergic neurons from inflammatory degeneration. Apparently, the neuroprotective effect of macelignan is mediated by PPARγ activation and arginase-1 expression. Macelignan inhibits LPS induced production of NO as well and inflammatory cytokines including TNF and IL- 1β in primary cultures of microglia.

Informations légales

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable