581424-U

Ascentis^® C8 (5 µm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

• Synonyme(s) : C8 Reversed-Phase Column
• Code UNSPSC : 41115700
• eCl@ss : 32110501
• Nomenclature NACRES : SB.52

Propriétés

• product name: Colonne Ascentis^® C8 pour HPLC, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
• Matériaux: stainless steel column
• Agence: suitable for USP L7
• Gamme de produits: Ascentis^®
• Caractéristiques: endcapped
• Fabricant/nom de marque: Ascentis^®
• Conditionnement: 1 ea of
• Ampleur du marquage: 15% Carbon loading
• Paramètres: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• Technique(s): HPLC: suitable; LC/MS: suitable
• L × D.I.: 15 cm × 4.6 mm
• Superficie: 450 m²/g
• Couverture de surface: 4.0 μmol/m²
• Impuretés: <5 ppm metals
• Matrice: fully porous particle; silica gel high purity, spherical
• Groupe de la matrice active: C8 (octyl) phase
• Taille des particules: 5 μm
• Dimension de pores: 100 Å
• operating pH range: 2-8
• Application(s): food and beverages
• Technique de séparation: reversed phase

Description

Description générale

L′Ascentis C8 est une colonne donnant des résultats hautement reproductibles avec une sélectivité excellente envers les composés polaires. La phase excelle dans des phases mobiles très aqueuses ainsi que dans des phases mobiles fortement organiques.

Application

• Analysis of 27 beta-Blockers and Metabolites in Milk Powder by High Performance Liquid Chromatography Coupled to Quadrupole Orbitrap High-Resolution Mass Spectrometry.: This study utilizes the Ascentis^® C8 HPLC Column to analyze beta-blockers and their metabolites in milk powder, highlighting the column′s capacity for sensitive and precise quantification in complex matrices (Cheng et al., 2019).


• Recent trends in ultra-fast HPLC: new generation superficially porous silica columns.: A review of advancements in HPLC technology, including the use of Ascentis^® C8 columns, which enhance the speed and efficiency of chemical separations (Ali et al., 2012).


• Superficially porous particles columns for super fast HPLC separations.: Discusses the benefits of using Ascentis^® C8 HPLC Columns for achieving faster and more efficient separations in HPLC, underlining their utility in high-throughput settings (Ali et al., 2012).


• Gradient RP-HPLC method for the determination of potential impurities in atazanavir sulfate.: Demonstrates the effectiveness of the Ascentis^® C8 HPLC Column in a robust method for identifying impurities in pharmaceutical compounds, ensuring product safety and compliance (Chitturi et al., 2011).


• Development and validation of an HPLC-MS/MS method to determine clopidogrel in human plasma. Use of incurred samples to test back-conversion.: Illustrates the application of Ascentis^® C8 HPLC Column in a validated method for the analysis of clopidogrel, improving therapeutic drug monitoring and patient care (Silvestro et al., 2010).

Caractéristiques et avantages

• Meilleure rétention des molécules hydrophobes
• Excellente forme du pic
• Séparations en LC-MS avec faible relargage

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Informations légales

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable